為什么使用自動(dòng)細(xì)胞培養(yǎng)器
為什么使用自動(dòng)細(xì)胞培養(yǎng)器
細(xì)胞生物學(xué)家使用細(xì)胞培養(yǎng)箱培養(yǎng)幾種不同類型的細(xì)胞,包括貼壁細(xì)胞、需要在CO2、飽和濕度或缺氧條件下保持的細(xì)胞系和組織。 這些細(xì)胞用于毒性研究、單克隆抗體生產(chǎn)、人類病毒疫苗生產(chǎn)、人工組織工程以及細(xì)胞和基因治療。 自動(dòng)化有助于增加產(chǎn)量,降低成本,并確保環(huán)境得到精確控制,沒(méi)有污染的風(fēng)險(xiǎn)。
在自動(dòng)細(xì)胞培養(yǎng)箱中尋找什么
自動(dòng)化細(xì)胞培養(yǎng)箱必須在細(xì)胞培養(yǎng)基中提供穩(wěn)定的溫度、無(wú)菌性、均勻性和穩(wěn)定的pH值(使用CO2氣體),并適合您的工作流程或液體處理站。
氣體氣氛控制-可選擇混合二氧化碳,氧氣,氮?dú)?,以?chuàng)建和保持適當(dāng)?shù)臍夥蘸蚿H值水平。 開(kāi)門(mén)后是否需要快速恢復(fù)氣氛? 可以選擇加油。
精確的溫度控制-選擇直接加熱的速度加熱和選擇消毒單位和水夾套加熱溫度均勻,并保持水無(wú)菌的附加措施。
濕度控制——你是通過(guò)減少氣流還是通過(guò)當(dāng)?shù)卮髿鈦?lái)控制濕度?
防止污染——當(dāng)門(mén)打開(kāi)和加熱夾套內(nèi)的水時(shí),需要保護(hù)樣品。
滿足您的需求——您的實(shí)驗(yàn)室可能需要一個(gè)小而靈活的培養(yǎng)箱,或者一個(gè)大而快,但不太通用的培養(yǎng)箱。
適合您的自動(dòng)化平臺(tái)和您的工作流程-對(duì)于大多數(shù)實(shí)驗(yàn)室來(lái)說(shuō),這意味著體積小,易于清潔和低維護(hù),具有自動(dòng)化選項(xiàng),包括自動(dòng)打開(kāi)/關(guān)閉和工作在一個(gè)通信標(biāo)準(zhǔn)。
使用INHECO SCILA CO2 4位培養(yǎng)箱
該SCILA經(jīng)Fraunhofer IPA/nICLAS獨(dú)立驗(yàn)證,可用于自動(dòng)工作流程中的自動(dòng)細(xì)胞培養(yǎng)和細(xì)胞分析。
閱讀INHECO SCILA上的夫瑯和費(fèi)國(guó)際IPA/nICLAS申請(qǐng)說(shuō)明
使用inheco scila實(shí)現(xiàn)基于細(xì)胞分析的自動(dòng)化
SCILA正在幫助傳染病專家研究瘧疾。
“SCILA孵化器與貝克曼液體處理器的集成非常優(yōu)雅。 SCILA是最小的細(xì)胞培養(yǎng)箱,也是世界上第一個(gè)用于瘧疾研究的血細(xì)胞培養(yǎng)自動(dòng)化解決方案。”
觀看Yifat Ofir Birin博士討論INHECO SCILA在瘧疾研究中的使用
https://www.youtube.com/watch?v=VHrgEYJtzLw
SCILA是一個(gè)非常緊湊的系統(tǒng),非常容易集成,非常適用于自動(dòng)化細(xì)胞培養(yǎng)。
Why use an automated cell incubator
Cell biologists use cell incubators to incubate several different cell types, including adherent cells, and cell lines and tissue that need to be kept under CO2 and saturated humidity, or hypoxic conditions. The cells are used in toxicity studies, monoclonal antibody production, human viral vaccine production, artificial tissue engineering, and cell and gene therapy. Automation helps increase throughput, reduce costs and ensure the environment is precisely controlled, without the risk of contamination.
What to look for in an automated cell incubator
An automated cell incubator must provide a stable temperature, sterility, homogeneity and stable pH value (using CO2 gas) across the cell culture medium, and fit into your workflow or liquid handling station.
Gas atmosphere control – with the option of mixing CO2, oxygen, nitrogen to create and maintain the appropriate atmosphere and pH levels. Do you need to quickly restore the atmosphere after opening the door? Look for gas boost as an option.
Precise temperature control – choose between direct heat for speed of heating and the option to sterilize the unit and water jacket heating for temperature uniformity, and additional measure to keep water sterile.
Humidity control – do you control it by minimizing airflow or through local atmosphere?
Protection from contamination – samples need protection when the door is open and from the water in the heating jacket.
Throughput that matches your needs – your lab may need an incubator that’s small and flexible or one that’s larger and faster, but less versatile.
Fits your automated deck and with your workflows – for most labs that means being small, easy to clean and low maintenance, with automation options including automatic opening/closing and working to a communication standard.
Use of the INHECO SCILA CO2 4-Position cell incubator
The SCILA is independently validated by Fraunhofer IPA/nICLAS for use in automated cell culture and cellular assays in automated workflows.
Read the Fraunhofer IPA/nICLAS application note on the INHECO SCILA
AUTOMATION OF CELL-BASED ASSAYS USING THE INHECO SCILA
The SCILA is helping infectious disease experts research malaria.
“The integration of the SCILA incubator in the Beckman's liquid handler is super elegant. SCILA is the smallest cell incubator and it's the world’s first automated solution used for blood cell cultivation in malaria research”
Watch Dr. Yifat Ofir Birin discuss the use of INHECO SCILA in malaria research
https://www.youtube.com/watch?v=VHrgEYJtzLw
“SCILA is an extremely compact system which is pretty easy to integrate & well applicable for automated cell culture”